… between geographic distribution of liver cancer incidence and the selenium (Se) contents
of … province, a high liver cancer area of the People's Republic of China. Animal experiments …

… have not found any widespread application in the treatment of established tumors. … 50% in
the liver tumor incidence compared with the control animals that received the basal diet during …

… as chemopreventive agents in several animal tumor models … will help to translate laboratory
findings into human application. … cell types in vitro including cells from the breast, lung, liver …

… animal models have shown that intake of selenium above … to show cancer chemopreventive
nature of selenium have been … ) on mouse skin tumor induced by the topical application of 2-(…

… , and has possible clinical applications in lung cancer patients [… of cancers, including
hepatocarcinoma [128,140], breast … useful in other cancer-related fields such as chemoprevention, …

… selenium chemopreventive agents than p-XSC for future application in preclinical assays and
subsequently in human … compounds as chemopreventive agents in laboratory animals [3]. …

… pathway in the soil, and animals and humans consume these sources as vegetables, meats…
and glycogen synthase kinase 3 beta in human liver cancer stem cells in vitro, which leads to …

… appears to be unrelated to chemoprevention [5, 17]. … Other preclinical animal models had
also been used to study the effect of selenium in liver cancer. Nine or thirteen weeks of sodium …

… that the chemopreventive efficacy of selenium depends on … of cancer prevention by selenium
is based on animal data and … of selenium-deficient rat liver resulted in down-regulation of …

Evidence from epidemiological studies and a human intervention trial indicates that selenium
(Se) may have chemopreventive activity in humans. This report summarizes a workshop …